北京协和医院妇产科张羽

这是一篇发表在2010年6月的《Obstet Gynecol》的综述性文章，今天太忙了，有时间翻译给大家看。

总的结论是：通过对来自136家研究数据的综合分析，认为，紧急避孕药不增加宫外孕的发病风险。

友情提示：紧急避孕药只能作为无保护性生活，或者避孕措施失败（例如安全套破裂）的补救措施。有规律性生活的女性不要作为常规避孕方式，可以选用短效口服避孕药，安全套，或者宫内节育器，具体的选择和适应症问题需要咨询专业的妇产科医生。

幸福生活，安全掌握。

原文摘要：

Obstet Gynecol. 2010 Jun;115(6):1263-6.

Ectopic pregnancy and emergency contraceptive pills: a systematic review.

Cleland K, Raymond E, Trussell J, Cheng L, Zhu H.

Office of Population Research, Princeton University, Wallace Hall, Princeton, New Jersey 08544, USA. kcleland@princeton.edu

Abstract

OBJECTIVE: To evaluate the existing data to estimate the rate of ectopic pregnancy among emergency contraceptive pill treatment failures.

DATA SOURCES: Our initial reference list was generated from a 2008 Cochrane review of emergency contraception. In August 2009, we searched Biosys Previews, the Cochrane Database of Systematic Reviews, Medline, Global Health Database, Health Source: Popline, and Wanfang Data (a Chinese database).

METHODS: This study included data from 136 studies, which followed a defined population of women treated one time with emergency contraceptive pills (either mifepristone or levonorgestrel) and in which the number and location of pregnancies were ascertained.

RESULTS: Data from each article were abstracted independently by two reviewers. In the studies of mifepristone, 3 of 494 (0.6%) pregnancies were ectopic; in the levonorgestrel studies, 3 of 307 (1%) were ectopic.

CONCLUSION: The rate of ectopic pregnancy when treatment with emergency contraceptive pills fails does not exceed the rate observed in the general population. Because emergency contraceptive pills are effective in lowering the risk of pregnancy, their use will reduce the chance that an act of intercourse will result in ectopic pregnancy。