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消化病学领域内基因芯片技术的应用(七)

(2010-03-18 12:52:18)
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基因芯片

微阵列芯片

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健康

分类: 医学临床诊断与科研服务芯片

消化病学领域内基因芯片技术的应用(七)

六、其他
(一)不同解剖部位和不同功能组织的区分
    Bates等用cDNA基因芯片杂交技术对比分析了成年大鼠消化道各部(胃、十二指肠、空肠、回肠、盲肠、近端结肠和远端结肠)基因表达谱的不同。结果显示,共有571项基因在消化道各部组织中的表达不完全一致,多数基因的表达有明显的阶段性变化。这些基因中变化最明显的是编码中间代谢、转运和细胞间信息传递功能蛋白的相关基因。结果提示,基因表达分析可以反应解剖学上的特征。同时发现了一些不明功能的新基因。表明基因芯片这一新兴的技术在发现新的功能基因方面提供了巨大的方便。
(二)肿瘤组织的分类
    Nguyen和Rocke的研究表明,基因芯片对不同肿瘤组织基因表达谱的分析资料进行聚类分析后可以对肿瘤组织的类型进行分类。各种基因表达谱亚型可能与肿瘤的临床相关的生物学特征、药物及其他关于处理措施可能存在密切的联系。经过进一步的完善,这种分类方法可能是对疾病诊断和治疗更有价值的分类方法。
    总之,基因芯片技术才刚刚渗入消化领域的研究,就已经显示了巨大的潜力和广阔的应用前景。这一新技术的介入,将对消化系统疾病发病机理、早期诊断、预后判断、病原微生物的致病基础、致病机理、毒力及耐药特征、药物作用机理、新药的开发利用、以及临床干预措施效果判断等领域的研究产生深远的影响。【提供服务:生物芯片整体解决方案、兽药残留芯片检测系统;生物芯片扫描仪等仪器;耳聋基因芯片、乙肝病毒耐药检测芯片、抗核抗体检测蛋白质芯片、结核分枝杆菌耐药检测芯片、G+细菌鉴定与耐药检测基因芯片等;食源性致病微生物检测试剂盒、兽药残留芯片检测试剂盒等;HLA基因分型检测方案、血小板基因分型;人类全基因组寡核苷酸微阵列芯片服务、家蚕全基因组寡核苷酸微阵列芯片服务、人肿瘤相关基因寡核苷酸微阵列芯片服务、miRNA微阵列芯片服务、DNA甲基化谱检测寡核苷酸芯片服务等;合作共建研究中心服务、生物芯片实验室建设服务、科研课题研究服务;糖尿病超强化治疗技术应用项目合作。请联系索取详细产品和服务介绍资料:医学与生命科学服务中心暨虫洞(北京)卫生科技有限公司,戴天岩  主任、总经理,手机:13051069337,E-mail:davad311@126.com,msn:davad311@hotmail.com,qq:104974415,虫洞医学与生命科学网http://blog.sina.com.cn/cnyr


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