德州医学中心拥有49家成员机构，大致分为以下三类：

医院和诊所

中心有两家综合医院和处理各方面问题的专科医院，包括儿童医院、肿瘤医院、心脏医院、器官移植、临终关怀、心理健康和预防保健等等。来自世界各地的病患在这里体验到最先进的医疗服务。

主要的医院有：

Baylor Clinic 贝勒医院

Harris County Hospital District 哈里斯郡医院区

The Houston Hospice and Palliative Care Systems  休斯顿安宁疗护系统  

Memorial Hermann-Texas Medical Center 休斯顿赫曼纪念医学中心

Children's Memorial Hermann Hospital 赫曼儿童纪念医院

The Methodist Hospital 卫理公会医院

St. Luke's Episcopal Hospital  圣卢克主教医院 

Shriners Hospitals for Children - Houston  休斯顿Shriners儿童医院

St. Dominic Village 圣道明庄

Texas Children's Hospital 德州儿童医院

TIRR (The Institute for Rehabilitation and Research) 康复研究医院

The University of Texas M. D. Anderson Cancer Center 德州大学安德森癌症中心

The University of Texas Medical Branch (UTMB) 德州大学医学部

Michael E. DeBakey Veterans Affairs Medical Center in Houston 休斯顿退役军人医学中心

学校和学术研究

德州医学中心是世界上许多著名医学研究学术机构的聚集地。主要的机构有：

Baylor College of Medicine

Michael E. DeBakey High School for Health Professions Michael E. DeBakey High School for Health Professions

Houston Academy of Medicine-Texas Medical Center Library Houston Academy of Medicine-Texas Medical Center Library

Houston Community College System Houston Community College System, Health Science Programs, Health Science Programs

The Methodist Hospital The Methodist Hospital

Prairie View A&M University Prairie View A&M University, College of Nursing, College of Nursing

Rice University Rice University

Texas A&M Health Science Center - Institute of Biosciences and Technology Texas A&M Health Science Center - Institute of Biosciences and Technology

Texas Heart Institute Texas Heart Institute

Texas Southern University College of Pharmacy & Health Sciences Texas Southern University College of Pharmacy & Health Sciences

Texas Woman's University Texas Woman's University Institute of Health Sciences-Houston Institute of Health Sciences-Houston

University of Houston University of Houston

University of Houston College of Pharmacy University of Houston College of Pharmacy

The University of Texas Medical Branch at Galveston The University of Texas Medical Branch at Galveston

The University of Texas Health Science Center at Houston The University of Texas Health Science Center at Houston

• Dental BranchDental Branch
• Graduate School of Biomedical Sciences Graduate School of Biomedical Sciences
• Harris County Psychiatric Center Harris County Psychiatric Center
• Medical School Medical School
• School of Health Information Sciences School of Health Information Sciences
• School of Nursing School of Nursing
• School of Public Health School of Public Health
• Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases

The University of Texas M. D. Anderson Cancer CenterThe University of Texas M. D. Anderson Cancer Center

其他机构

为提高行政系统与研究机构的配合，政府行政机构亦就近设立于医学中心，如休士顿卫生福利局、哈礼斯郡医学检察局等。还有许多其他的机构，如药学院、精神病与健康研究中心、采血库、医学图书馆，甚至洗衣店等各种辅助设施，为居住在这里和周围的人们提供更多的便利。

City of Houston Department of Health and Human Services

Gulf Coast Regional Blood Center

Harris County Medical Society

Harris County Public Health and Environmental Services

Houston Academy of Medicine

Houston Academy of Medicine - Texas Medical Center Library

The Institute for Spirituality and Health

Harris County Institute of Forensic Sciences

LifeGift

Ronald McDonald House of Houston, Inc.

John P. McGovern Museum of Health and Medical Science

Texas Medical Center (corporation)

Thermal Energy Corporation

Texas Medical Center Hospital Laundry Cooperative Association

YMCA Child Care Center at the Texas Medical Center