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我要和食物过敏死磕到底!

(2013-08-14 09:01:55)
分类: baby

MANAGEMENT OF ALLERGIC COLITIS IN BREASTFED INFANTS

Though babies cannot be allergic to human proteins, they can be allergic to the 
foreign food antigens that are present in human milk, due to maternal food 
ingestion. This article focuses on allergic colitis (also known as allergic 
proctocolitis) , a Type IV hypersensitivity reaction that can occur in both infant 
formula fed and breastfed infants. It does not cover IgE mediated allergies where 
hives angioedema and anaphylaxis may be possible symptoms.

Typical symptoms allergic colitis may include fussiness, excessive watery stools, 
stools that are dark (orange, green, brown) when the expected color would be 
yellow, and even blood or mucus in the stool. Occasionally, an infant will have 
skin breakdown in the perianal area (known as erosive dermatitis) that will not go 
away until the offending antigen is taken out of the diet. Up to half of infants with 
allergic colitis may show additional signs of gastroesophageal reflux (GERD). 
Common signs of GERD include discomfort during or after feedings, body arching 
or fussiness when laid flat. 

Treatment of allergic colitis consists of a maternal elimination diet. There are 
several dietary approaches. Most mothers eliminate dairy and soy, because cow 
milk and soy foreign antigens in human milk most commonly cause infant food 
allergy symptoms. If a mother does not think that elimination of both dairy and 
soy is feasible, she should start with elimination of cow milk products first. Some 
experts recommend simultaneously eliminating cow meat products as well.

Once the offending antigen is eliminated from the diet, parents should be aware 
that symptoms will gradually improve, usually starting around 5 days after the 
offending agent is eliminated. It may take up to three weeks for diarrhea and 
bloody stools to completely resolve. 

If an infant continues to have frequent stools, ask the mother to check for hidden 
soy and dairy products (see table 1). Foods and medications- especially prenatal 
vitamins- should be checked for hidden products (such as casein, whey and lactose
in the case of cow milk food additives). Mothers should be informed that lecithin is 
a soy-derived food additive. Most of the time, elimination of hidden ingredients
will result in symptom improvement. Mothers on a dairy and soy-free diet will 
often want to know what they can consume (“what’s left?”). Table 2 lists foods 
that she can eat on a soy and dairy-free diet. If there still is no improvement, 
elimination of nut products would be next, followed by wheat, and so on. Food 
elimination advances every 5 to 7 days, if no noticeable improvement is noted.

TABLE 1
Cow-based Hidden 
Ingredients
Butter 
Butter fat 
Butter solids 
Butter flavor
Buttermilk 
Calcium caseinate
Caramel color
Caramel flavoring 
Casein 
Caseinate 
Dried milk 
Galactose
Lactalbumin
Lactate
Lactoferrin
Lactoglobulin
Lactose 
Milk
Milk fat
Milk protein 
Milk solids 
Naturlose
Opta Recaldent
Simplesse
Sour cream
Sour milk solids 
Tagatose 
Whey
Yogurt



Table 2
Breastfeeding moms on a dairy and soy-free diet can eat the following foods:
 All vegetables except for soy. Some super-sensitive babies may also show a 
sensitivity to "cousins" of soy such as peas or peanuts
 All fruits
 All meats except for beef products
 All grains
 Eggs-occasionally a baby will show some sensitivity, but the majority of the time 
infants will tolerate this maternal food ingestion

Keep in mind the following:
 Be sure to check food labels for evidence of soy or dairy products every time
 Remember to check the hidden ingredient sheet for hidden dairy products
 Hidden soy ingredients can be listed as lecithin or soy lecithin
 Relapses will sometimes occur after moms have dined out or have consumed 
prepared foods from the grocer
 Vegetable oils often contain soy and are used in some prepared foods
 Some helpful websites include:
Enjoylifefoods.com
Foodallergynetwork.org

Assuming that the infant improves with maternal elimination of soy and dairy, the 
mother can attempt to add small amounts of either soy or dairy into her own diet 
after about one to two months of restricted diet. Her diet would need to revert back 
to the stricter regimen if, while reintroducing the food product, her infant again 
displays fussiness and adverse stool changes over the next five days.

If it is difficult to identify the offending agent, some mothers are willing to place 
themselves on a strict elimination diet. This includes either a rice and turkey or a 
rice and lamb diet. She needs to be sure no other additives are used in preparing 
these foods. After strict adherence for 5 days she then adds one additional food
product that is neither dairy or soy to her diet. Some examples would include a 
specific vegetable, fruit or oatmeal. Then she observes the infant for symptoms for 
5 days. If there is no adverse response, she repeats the same process of adding a 
food every five days while observing the infant for symptoms.

An alternative to this strict diet is to eliminate all common offenders and slowly 
add them back. This would include eliminating cow products, soy, citrus fruits, 
eggs, nuts, peanuts, wheat, corn, strawberries and chocolate. One ingredient is 
added every 5-7 days 

The mother should be on a multivitamin with minerals while on a restricted diet. 
This usually entails finding a product that does not include hidden additives that 
she is trying to avoid. An online search is often helpful. She should consume 
1000mg of calcium a day (many calcium products are not cow derived but she 
should check with the manufacturer).

If signs of GERD are also present, infant positioning and even ranitidine may be 
needed; however, GERD symptoms may improve in some infants a few weeks 
after the problem antigen is eliminated. Some infants may only need ranitidine for 
a month, while for others, treatment until six to twelve months of age may be 
necessary.

Infants will sometimes experience a setback. For instance, a mother may 
unknowingly ingest a food containing the offending antigen while dining outside 
the home. Restaurant personnel may not be entirely aware of hidden ingredients in 
their own products. Prepared foods at the grocer may not be accurately labeled. For 
example, a label for rotisserie chicken might only state that it is cooked with 
vegetable oil, though the oil is partially derived from soy. Another setback can 
occur after solids are introduced. It is important for parents to check for trace 
elements in infant baby food. Most baby food manufacturers have helpful charts on 
their website that will list trace ingredients. 

As with infant formula allergies, most breastfed infants with food 
hypersensitivities will experience resolution of their allergy between 12 and 18
months of age. The process of introduction of a small amount of product as a trial 
is generally the same.

Allergic colitis does occasionally occur in breastfed infants. Determined mothers 
can successfully modify their diets in order to eliminate infant symptoms. The 
majority of infants will eventually outgrow their food sensitivity.

©Diana Mayer, MD, IBCLC

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