Abstract 

摘  要

Laser therapy is becoming common place in veterinary medicine with little evidence proving efficacy or dosages. This study evaluated surgical wound healing in canines.

激光疗法在兽医学中越来越普遍，但几乎没有相关试验证据证明其功效或规范治疗剂量。这项研究评估了使用激光治疗犬的手术伤口愈合情况。

Twelve Dachshunds underwent thoraco-lumbar hemilaminectomies for intervertebral disc disease (IVDD). Digital photographs were taken of their incisions within 24 h of surgery and 1, 3, 5, 7, and 21 days postoperatively. The first three dogs were used to create a standardized scar scale to score the other dogs' incision healing. The remaining 9 dogs were randomly assigned to either receive 8 J/cm2 laser therapy once a day for 7 days or the non-laser treated control group. 

12 只腊肠犬因椎间盘疾病 (IVDD) 接受了胸腰椎半椎板切除术。在手术后 24 小时内和术后 1、3、5、7 和 21 天拍摄他们切口的照片。根据前三只狗的切口愈合情况制作一个标准化的疤痕量表，作为评分标准，以此来评估其他狗的切口愈合情况。其余9只狗被随机分为两组，一组接受8J/c激光治疗，每天一次，持续7天；另一组作为对照组接受非激光治疗。

Incision healing was scored based on the scar scale from 0 to 5, with zero being a fresh incision and five being completely healed with scar contraction and hair growth. All scar scores significantly improved with increasing time from surgery (<0.001). Good agreement was achieved for inter-rater reliability (p = 0.9). 

切口愈合评分表根据疤痕收缩状态和毛发生长情况，从0到5分为5个等级，0为新鲜切口，5为完全愈合。随着手术后治疗时间的增加，所有疤痕状态均显著改善（<0.001）。评估者间可靠性取得了良好的一致性（p=0.9）。

Laser therapy increased the scar scale score, showed improved cosmetic healing, by day seven and continued to be significantly increased on day 21 compared to control dogs (p < 0.001). 

激光治疗提高了疤痕量表的评分数值，与对照犬相比，到第七天展现出更优的切口愈合外观。一直到第21天，疤痕量表评分数值继续显着增加（p<0.001）。

Daily application of laser therapy at 8J/cm2 hastened wound healing in Dachshunds that received thoracolumbar hemilaminectomies for IVDD. It also improved the cosmetic appearance.

由实验结果推导出结论：每天使用8J/c的激光治疗加速了因IVDD接受胸腰椎半椎板切除术的腊肠犬的伤口愈合，它还减少了疤痕增生。

Figure 1 

Examples of the scar scale images used for reviewer ranking of surgical incisions for both treatment groups. (A) This image was defined as a scar scale score of zero. (B) This image was defined as a scar scale score of five.

图1。用于评估两组手术切口愈合状况等级评分表的例子。(A)在等级评分表中该图像被定义为分0。(B)在等级评分表中此图像定义为5分。

Figure 2 

Representative images of the two treatments groups at day 21. (A) A non-laser patient illustrating the continued presence of a scab over some of the incision's epithelium. (B) A non-laser patient with a wide scar area and one remaining pink area of granulation toward the right side of the incision. (C) A laser therapy patient showing a completely healed incision with contraction and hair regrowth around and on the incision.

图2。两个治疗组在第21天的代表性照片。(A)一名非激光患者，作为标准化疤痕量表，显示在治疗21天时部分切口上还存在痂皮。(B)非激光患者，切口右侧有一个宽疤痕区和一个粉红色肉芽区。(C)激光治疗患者显示切口完全愈合，切口周围有毛发再生。

Figure 3 

Frequency histogram showing individual scar scale scores (n = 48) on day 21 for the low intensity laser therapy (n = 3) and non-laser treatments (n = 5) groups from the six veterinary reviewers.

图 3。频率直方图显示了来自6位兽医评审员对激光治疗 (n=3) 和非激光治疗 (n=5) 组在第21天的个体疤痕评分 (n=48)。

所有图片及文字内容均引自本次分享的文献：《Laser Therapy for Incision Healing in 9 Dogs》Jennifer L. Wardlaw, Krista M. Gazzola, Amanda Wagoner, Erin Brinkman, Joey Burt, Ryan Butler, Julie M. Gunter and Lucy H. Senter