问题：

dubug时出现以下现象：

“TestIfly.exe”: 已加载“E:\workspace\vc\TestIfly\Debug\TestIfly.exe”，已加载符号。
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\ntdll.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\kernel32.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\KernelBase.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\InterReco 4.1\bin\isr_api.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\user32.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\gdi32.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\lpk.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\usp10.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\msvcrt.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\advapi32.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\sechost.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\rpcrt4.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\sspicli.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\cryptbase.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\winsxs\x86_microsoft.vc80.crt_1fc8b3b9a1e18e3b_8.0.50727.4927_none_d08a205e442db5b5\msvcp80.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\winsxs\x86_microsoft.vc80.crt_1fc8b3b9a1e18e3b_8.0.50727.4927_none_d08a205e442db5b5\msvcr80.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\version.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\msvcr100d.dll”，已加载符号。
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\imm32.dll”，Cannot find or open the PDB file
“TestIfly.exe”: 已加载“C:\Windows\SysWOW64\msctf.dll”，Cannot find or open the PDB file
程序“[8868] TestIfly.exe: 本机”已退出，返回值为 126 (0x7e)。

参照：http://topic.csdn.net/u/20101108/14/49f2a594-8da2-4f5e-a01d-dd08b29f961b.html

总结如下:

原因是程序输出的地方是系统而不是vs2010。
Ctrl + F5运行就可以了
或者在cmd命令行下执行程序。

或者

把"Microsoft Symbol Servers"勾上(Tools -> Options -> Debugging -> Symbols).