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R语言 preprocessCore包 normalize.quantiles()

(2015-04-22 17:00:24)
标签:

分位数标准化

nomalize

quantiles

normalize.quantiles {preprocessCore}

Quantile Normalization

package install

source("http://bioconductor.org/biocLite.R")
Bioconductor version 2.12 (BiocInstaller 1.10.3), ?biocLite for help
biocLite("preprocessCore")

library(preprocessCore)

Description

Using a normalization based upon quantiles, this function normalizes a matrix of probe level intensities.

Usage

  normalize.quantiles(x,copy=TRUE)

Arguments

x

A matrix of intensities where each column corresponds to a chip and each row is a probe.

copy

Make a copy of matrix before normalizing. Usually safer to work with a copy, but in certain situations not making a copy of the matrix, but instead normalizing it in place will be more memory friendly.

 eg


> a<-matrix(1:6,3,2)
> a
     [,1] [,2]
[1,]      4
[2,]      5
[3,]      6

> library(preprocessCore)
> b=normalize.quantiles(a)
> b
     [,1] [,2]
[1,]  2.5  2.5
[2,]  3.5  3.5
[3,]  4.5  4.5


 

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