最近有文献报告了研究人员对45000多名成人长期随访的结果，发现“心功能不全或心力衰竭者易骨质疏松”，这是一个值得关注的倾向，因为随着人寿的增长和高血压、冠心病等患病率的不断攀升，心力衰竭的病人将会越来越多，故应重视这一部分人之骨质疏松的防治。为何心功能不全者易患骨质疏松？本人认为可能与以下几个因素有关：

一是因受到心功能不全之影响，患者往往极少从事体育锻炼，故易患骨质疏松；

二是心功能不全可影响胃肠功能，即可能影响钙和维生素Ｄ的吸收，故易患骨质疏松。

三是因心功能不全导致的人体水钠过多可能影响患者的内分泌，甚至影响肝肾功能进行影响维生素Ｄ的活化，故易患骨质疏松。

Heart Failure, Osteoporosis Go 'Hand-in-Hand': Researchers

Cardiac condition raises the risks of falls and may contribute to bone-density loss

TUESDAY, Feb. 7 (HealthDay News) -- Heart failure is linked to thinning of the bones and an increased risk of fractures, a new study indicates.

The findings suggest that aggressive screening for osteoporosis may be important for heart failure patients, the researchers said.

They looked at data from about 45,500 adults who underwent bone mineral density testing for the first time and were followed for up to 10 years. Of those people, 1,841 had recent-onset heart failure.

After the researchers adjusted for traditional osteoporosis risk factors, they concluded that heart failure was associated with a 30 percent increased risk of major fractures.

The study will be published in the April issue of the Journal of Clinical Endocrinology & Metabolism.

"Our study demonstrates for the first time that heart failure and thinning of bones go hand in hand," study author Dr. Sumit Majumdar, of the University of Alberta in Edmonton, Canada, said in a journal news release. "Understanding the mechanism between heart failure and osteoporosis might lead to new treatments for both conditions."

He suggested that osteoporosis screening should include examining chest X-rays of patients with heart failure.

"Heart failure patients get a lot of X-rays and they often incidentally show many fractures of the spine that would automatically provide an indication of severe osteoporosis and need for treatment," Majumdar said.

SOURCE: Journal of Clinical Endocrinology & Metabolism, news release, Feb. 2, 2012