最近，英国学者公布了1998～2009年间观察的资料，即通过比较432例多发性硬化症女性和近3000例健康女性之妊娠和胎儿分娩情况后发现，大多数患多发性硬化症的女性能够安全怀孕和分娩。研究人员同时还注意到，患多发性硬化症的女性若超重或肥胖者，怀孕和分娩时则可增加风险，故此类女性在妊娠过程中应注意体重管理，如减肥或避免超重等。

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Pregnancy Safe for Most Women With MS: Study

But researchers advise losing any excess weight before conceiving

MONDAY, June 27 (HealthDay News) -- Pregnancy is generally safe for women with multiple sclerosis, a new study says.

Canadian researchers analyzed 432 births to women with MS and almost 3,000 births to women without MS in the province of British Columbia between 1998 and 2009. They found no significant differences in either timing of delivery or birth weight between babies born to women with MS and babies born to mothers without the illness.

The likelihood of vaginal or caesarian delivery was the same for both groups of women, but mothers with MS who had greater levels of disability had a slightly elevated risk of adverse delivery outcomes. However, the difference was not statistically significant and further research is needed, the study authors said.

"Our finding that MS was not associated with poor pregnancy or birth outcomes should be reassuring to women with MS who are planning to start a family," study author Mia van der Kop, a member of the MS research group at the University of British 　Columbia and Vancouver Coastal Health Research Institute, said in a journal news release.

Her team noted that women with MS were more often overweight or obese, which is associated with greater risk during pregnancy and birth. These women should ideally lose weight before they become pregnant, the researchers suggested.

The study is published June 27 in the journal Annals of Neurology.

SOURCE: Annals of Neurology, news release, June 27, 2011