Differential Diagnosis

• infectious or non-infectious airway-associated disease (allergic bronchitis, eosinophilic bronchopneumopathy)

Diagnosis

Bronchial lavage: Marked eosinophilic inflammation with increased mucus

Pathology Comments:Differentials include hypersensitivity/allergic response, primary eosinophilic pulmonary granulomatosis or inflammation secondary to underlying infectious disease including fungal, atypical bacterial or parasitic causes. Paraneoplastic responses can also lead to eosinophilic inflammation although this is thought to be less likely in this case. No infectious agents or overtly neoplastic cells are observed.