Functions FirmingSmoothingAnti-aging

INCI name Elaidoyl Tripeptide-37

Elaidoyl Tripeptide-37 is a synthetic lipo-peptide with sequence Elaidyl-KFK (Elaidyl-Lys-Phe-Lys-OH) known under the trade name Lipospondin. It is an ester of elaidic acid and Tripeptide-37 (KFK peptide), which repeats a part of the sequence of Thrombospondin.

Thrombospondins are proteins that activate TGF (transforming growth factor), boosting ECM (extracellular matrix) component production and playing an important role in angiogenesis, ECM assembly, and tissue remodeling. Tripeptide-37 stimulates TGF-β, promoting collagen and elastin production by fibroblasts.

The lipophilic part of Elaidoyl Tripeptide-37 elaidic acid inhibits and downregulates MMP-1 (including MMP-2, MMP-9, and MMP-3), metalloproteinase enzymes responsible for collagen destruction, upregulating collagen, and other structural proteins in ECM and boosting repair processes in the skin.

*来源成都云熙化工有限公司蒋