加载中…“大力水手”成真了？这项研究用菠菜让细胞“返老还童”
(2023-12-19 12:14:06)
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可可英语菠菜光合作用类囊体 |
分类： 转载 |
A plant-derived natural
photosynthetic system for improving cell
anabolism.
“大力水手”成真了？这项研究用菠菜让细胞“返老还童”
Photosynthesis is a unique
skill of green plants – they turn water and carbon dioxide into
oxygen and food via sunlight.
光合作用是绿色植物的一项独特技能——植物通过阳光将水和二氧化碳转化为氧气和食物。
A group of Chinese
scientists, however, have “copied” the process on
animals.
然而，一个中国科学团队在动物身上“复制”了这一过程。
To understand the new
breakthrough, it is important to know how photosynthesis
works.
要想理解这个新的突破，重点要了解光合作用如何运作。
Plants take in carbon
dioxide and water from the air and soil.
植物从空气和土壤中吸收二氧化碳和水。
Within the plant cell, the
water is oxidized. This transforms the water into oxygen and the
carbon dioxide into glucose.
在植物细胞内，水氧化并转化为氧气，而二氧化碳转化为葡萄糖。
The plant then releases the
oxygen back into the air and stores energy within the glucose
molecules.
随后植物将氧气释放回空气中，并将能量储存在葡萄糖分子内。
In the study, the
researchers from Zhejiang University developed an independent and
controllable photosynthetic system, according to the study
published in Nature in early December, 2022.
该研究发表于2022年12月初的《自然》杂志上，浙江大学的研究人员开发了一套独立、可控的光合作用系统。
They separated thylakoids, a
part of the cell where light reactions take place in plants, from
young spinach leaves. The scientists then wrapped the thylakoids
with the cover of animal cells, which made the implanted thylakoids
more acceptable to foreign bodies.
研究团队从菠菜嫩叶中分离出参与光合作用的类囊体，再用动物自身的细胞膜来包裹类囊体，借助这层伪装，让植入的类囊体更容易为相异的细胞所接受。
The mice used in the study
were suffering from arthritis, meaning cells in their cartilage had
degenerated and could not be repaired by
themselves.
在这项研究中，研究者以骨关节炎小鼠模型为例进行了探索，这些小鼠的软骨细胞已经退变、老化，无法自行修复。
With the thylakoids
implanted into the mice and exposed to light, the mice recovered.
Their metabolism returned to normal.
研究人员将类囊体植入小鼠体内，并施加光照，小鼠的关节健康状况因此得到明显改善，细胞的合成代谢也恢复正常。
In arthritis, patients
usually have energy loss since fewer energy-carrying molecules are
generated.
如果患有骨关节炎，由于新生的载能分子较少，患者通常会产生能量损失。
The implant, however, can
correct the imbalance by storing more energy via
photosynthesis.
然而，植入的类囊体可以通过光合作用储存更多能量，扭转这一失衡状态。
The researchers also claimed
that their tests would have medical usage. It can be used as part
of the solution for degenerative diseases because the natural
photosynthesis system may repair cells. It may also delay the aging
process in cells.
研究人员还表示，这项测试将具有医疗用途，由于植物天生的光合作用系统可以修复细胞，该研究适用于退行性疾病的治疗策略，还有望延缓细胞的衰老。
The study showed “an
exciting achievement that opens up possibilities of metabolism
engineering,” commented one of the paper’s reviewers Francisco
Cejudo from the University of Seville in Spain, reported
Xinhua.
据新华社报道，来自西班牙塞维利亚大学的论文同行评审弗朗西斯科?塞朱多认为，该研究“是一项令人兴奋的成就，开辟了代谢工程的可能性。”
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