加载中…
个人资料
赤脚神游天下
赤脚神游天下
  • 博客等级:
  • 博客积分:0
  • 博客访问:8,563
  • 关注人气:7
  • 获赠金笔:0支
  • 赠出金笔:0支
  • 荣誉徽章:
相关博文
推荐博文
谁看过这篇博文
加载中…
正文 字体大小:

NAVA能够改善气管插管自主呼吸患者人机同步性

(2011-02-15 15:45:43)
标签:

nava

ps

同步性

icu

分类: ICM

Neurally adjusted ventilatory assist improves patient–ventilator interaction

Lise Piquilloud, Laurence Vignaux, Emilie Bialais, Jean Roeseler, Thierry Sottiaux, Pierre-François Laterre, Philippe Jolliet, Didier Tassaux
Volume 37, Issue 2 / February , 2011 Pages 263 - 271

 

Purpose

To determine if, compared with pressure support (PS), neurally adjusted ventilatory assist (NAVA) reduces trigger delay, inspiratory time in excess, and the number of patient–ventilator asynchronies in intubated patients.

NAVA(神经调节通气辅助)与PS模式比较,前者在气管插管患者中更好的减少触发延迟,吸气时间,改善人机同步性。

Methods

Prospective interventional study in spontaneously breathing patients intubated for acute respiratory failure. Three consecutive periods of ventilation were applied: (1) PS1, (2) NAVA, (3) PS2. Airway pressure, flow, and transesophageal diaphragmatic electromyography were continuously recorded.

前瞻性研究急性呼吸困难插管的自主呼吸患者。先后使用三种呼吸模式PS1,NAVA,PS2,并连续记录气压,气流,经食道膈肌肌电图。

Results

All results are reported as median (interquartile range, IQR). Twenty-two patients were included, 36.4% (8/22) having obstructive pulmonary disease. NAVA reduced trigger delay (ms): NAVA, 69 (57–85); PS1, 178 (139–245); PS2, 199 (135–256). NAVA improved expiratory synchrony: inspiratory time in excess (ms): NAVA, 126 (111–136); PS1, 204 (117–345); PS2, 220 (127–366). Total asynchrony events were reduced with NAVA (events/min): NAVA, 1.21 (0.54–3.36); PS1, 3.15 (1.18–6.40); PS2, 3.04 (1.22–5.31). The number of patients with asynchrony index (AI) >10% was reduced by 50% with NAVA. In contrast to PS, no ineffective effort or late cycling was observed with NAVA. There was less premature cycling with NAVA (events/min): NAVA, 0.00 (0.00–0.00); PS1, 0.14 (0.00–0.41); PS2, 0.00 (0.00–0.48). More double triggering was seen with NAVA, 0.78 (0.46–2.42); PS1, 0.00 (0.00–0.04); PS2, 0.00 (0.00–0.00).

Conclusions

Compared with standard PS, NAVA can improve patient–ventilator synchrony in intubated spontaneously breathing intensive care patients. Further studies should aim to determine the clinical impact of this improved synchrony.

和标准的PS相比,NAVA能够改善气管插管自主呼吸患者人机同步性。还需要更多的研究这种人机同步性改善后对临床的影响。

0

阅读 评论 收藏 转载 喜欢 打印举报/Report
  • 评论加载中,请稍候...
发评论

    发评论

    以上网友发言只代表其个人观点,不代表新浪网的观点或立场。

      

    新浪BLOG意见反馈留言板 电话:4000520066 提示音后按1键(按当地市话标准计费) 欢迎批评指正

    新浪简介 | About Sina | 广告服务 | 联系我们 | 招聘信息 | 网站律师 | SINA English | 会员注册 | 产品答疑

    新浪公司 版权所有