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Microstates of EEG

(2015-02-10 21:02:33)
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股票

分类: EEG
Microstates are defined by topographies of electric potentials over a multichannel electrode array over scalp, which remain stable for 80-120ms. [1]

我认为这是下一个研究的热点,因为microstate恰恰说明了大脑既是dynamic又是stable。
microstates目前主要是sensor space。
既可以与fMRI结合,探索大脑的resting state network[2,3],又可以做到source space。
应用于大脑工作原理的探索,认知功能和疾病[4,5]检测。



An example (256-channel resting EEG, collected by EGI system)
Microstates <wbr>of <wbr>EEG



Reference
[1] Khanna, A., Pascual-Leone, A., Michel, C. M. & Farzan, F. Microstates in resting-state EEG: Current status and future directions. Neuroscience and biobehavioral reviews 49C, 105-113, doi:10.1016/j.neubiorev.2014.12.010 (2015).
[2] Yuan, H., Zotev, V., Phillips, R., Drevets, W. C. & Bodurka, J. Spatiotemporal dynamics of the brain at rest--exploring EEG microstates as electrophysiological signatures of BOLD resting state networks. NeuroImage 60, 2062-2072, doi:10.1016/j.neuroimage.2012.02.031 (2012).
[3] Lehmann, D. Multimodal analysis of resting state cortical activity: what does fMRI add to our knowledge of microstates in resting state EEG activity? Commentary to the papers by Britz et al. and Musso et al. in the current issue of NeuroImage. NeuroImage 52, 1173-1174, doi:10.1016/j.neuroimage.2010.05.033 (2010).
[4] Kindler, J., Hubl, D., Strik, W. K., Dierks, T. & Koenig, T. Resting-state EEG in schizophrenia: auditory verbal hallucinations are related to shortening of specific microstates. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 122, 1179-1182, doi:10.1016/j.clinph.2010.10.042 (2011).
[5] Andreou, C. et al. Resting-state connectivity in the prodromal phase of schizophrenia: insights from EEG microstates. Schizophrenia research 152, 513-520, doi:10.1016/j.schres.2013.12.008 (2014).

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