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宫颈上子宫切除术是卵巢癌治疗的选择之一

(2007-04-21 23:26:00)
 

 

Supracervical Hysterectomy Alternative for Ovarian Cancer

宫颈上子宫切除术是卵巢癌治疗的选择之一
NEW YORK (Reuters Health) Mar 22 - Supracervical hysterectomy may be a reasonable alternative to total abdominal hysterectomy for women with advanced epithelial ovarian cancer, according to a report in the March Obstetrics & Gynecology.

路透社健康纽约3月22日电-根据三月份《产科学和妇科学》的一份报告,宫颈上子宫切除术或许成为需行经腹全子宫切除术的晚期卵巢上皮性癌女性患者合理的替代手段。
Although oncologists have traditionally recommended total abdominal hysterectomy for women with ovarian cancer, the authors explain, many oncologists now recommend supracervical hysterectomy for those who will receive intraperitoneal chemotherapy because it may limit vaginal leakage of the chemotherapeutic agents.

尽管肿瘤专家传统上建议卵巢癌妇女行经腹全子宫切除术,作者解释,许多肿瘤专家现在建议那些即将接受腹腔化疗的(卵巢癌妇女)接受宫颈上子宫切除术,因为这种手术也许可以限制化疗药物阴道渗漏。
Dr. Pedro T. Ramirez from University of Texas M. D. Anderson Cancer Center, Houston, and associates compared clinical outcomes in 47 women who underwent supracervical hysterectomy and 190 women who underwent total abdominal hysterectomy for advanced ovarian cancer.

来自休斯敦德州大学安德森癌症中心的佩德罗-莱米蕾丝医生和同事对两组行不同术式晚期卵巢癌妇女的临床结果进行比较,其中47例妇女行宫颈上子宫切除术,190例妇女行经腹全子宫切除术。
Although intraoperative complications did not differ between the two groups, the authors report, a greater proportion of women who underwent total abdominal hysterectomy had optimal tumor cytoreduction (64.7% versus 30% for supracervical hysterectomy).

作者报告称,尽管在两组间术中并发症没有差别,但获得较理想肿瘤细胞减灭作用在行经腹全子宫切除术妇女中比率更大(与宫颈上子宫切除术妇女比例为64.7%对30%)。
The two groups did not differ significantly in progression or rates of recurrence, vaginal bleeding, vaginal discharge or and dysuria during follow-up.
Overall survival and progression-free survival also did not differ in the two groups, the researchers note.

在随访中两组在复发率、进展、阴道出血,阴道分泌物和/或拍尿困难上没有显著差异。研究人员提到,在两组中总生存期和无进展生存也没有差异。
There were no difficulties in physical examinations due to the presence of the cervical stump in the supracervical hysterectomy group and fewer cases of tumor erosion into the vagina compared with the total abdominal hysterectomy group.

不存在宫颈上子宫切除术后留有的子宫残蒂导致身体检查困难,与经腹全子宫切除术组相比有少量肿瘤侵蚀阴道病例。
"At present, supracervical hysterectomy is not routinely performed or recommended at M. D. Anderson Hospital," the investigators note. "However, supracervical hysterectomy may merit further consideration given the findings of our present study and the recent findings of improved survival in patients treated with intraperitoneal chemotherapy for ovarian cancer."

“目前,安德森医院不建议或常规行宫颈上子宫切除术”研究人员指出。“然而,假设发现我们目前研究和最近的发现证实卵巢癌患者加用腹腔化疗可改善生存率,宫颈上子宫切除术也许值得进一步考虑。”
"The option of supracervical hysterectomy should be reviewed with patients preoperatively during a discussion of potential indications for and benefits of different surgical techniques," the researchers conclude.
Obstet Gynecol 2007;109:641-646.

研究人员总结道:“在患者术前不同外科技术的潜在适应症和受益的讨论过程中,宫颈上子宫切除术的选择应予评估。”

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