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研究表明DNA不能解释所有的遗传特征

(2015-04-08 16:26:09)
标签:

遗传

健康

分类: 每日新闻

新闻翻译第1163贴   20150408

DNA can't explain all inherited biological traits, research shows

研究表明,DNA不能解释所有的遗传特征

 

Characteristics passed between generations are not decided solely by DNA, but can be brought about by other material in cells, new research shows.

据《每日科学》网站4月2日报道,英国科学家最新研究结果显示,父子辈的遗传特征并非独由DNA决定,细胞内的其它物质也可承担此任务。

 

Scientists studied proteins found in cells, known as histones, which are not part of the genetic code, but act as spools around which DNA is wound. Histones are known to control whether or not genes are switched on.

科学家们研究了细胞中发现的蛋白—组蛋白,它不是遗传密码的一部分,但却扮演着缠绕在受伤DNA周围的角色。已经得知组蛋白可调控基因,无论基因是否被打开。

 

Researchers found that naturally occurring changes to these proteins, which affect how they control genes, can be sustained from one generation to the next and so influence which traits are passed on.

研究人员发现,组蛋白自然发生的变化可从一代持续到下一代,从而影响被遗传的特征。组蛋白的自然变化影响它们控制基因的方式。

 

The finding demonstrates for the first time that DNA is not solely responsible for how characteristics are inherited. It paves the way for research into how and when this method of inheritance occurs in nature, and if it is linked to particular traits or health conditions.

这一发现首次证实,DNA不是唯一负责遗传的物质。为研究该遗传方法如何和何时自然发生以及它是否与特殊特征或健康条件有关等问题铺平了道路。

 

It may also inform research into whether changes to the histone proteins that are caused by environmental conditions -- such as stress or diet -- can influence the function of genes passed on to offspring.

还可以对由环境条件(如压力或者饮食)引起的组蛋白变化进行研究,看看这些变化是否能影响遗传给下一代的基因的功能。

 

The research confirms a long-held expectation among scientists that genes could be controlled across generations by such changes. However, it remains to be seen how common the process is, researchers say.

研究人员称,研究证实了科学家们长久以来的期望:世代基因能够被这样的变化所控制。然而,还要看一看这一过程有多普遍。

 

Scientists tested the theory by carrying out experiments in a yeast with similar gene control mechanisms to human cells. They introduced changes to a histone protein, mimicking those that occur naturally, causing it to switch off nearby genes. The effect was inherited by subsequent generations of yeast cells.

科学家们在与人类细胞基因控制机制相似的酵母中做实验,来验证该理论。他们促使一个组蛋白发生变化,模仿那些导致其基因关闭的自然发生的变化。通过酵母细胞的后代,这种效果被遗传下来。

 

 

http://www.sciencedaily.com/releases/2015/04/150402161751.htm

 

 

 

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